Weight, appetite, leanness
Peptides for fat loss
Sorted by strength of evidence, never by popularity. A higher grade means stronger proof, not that something is safe or right for you.
12 profiles
Large human trials
6- A
Research compound
Cagrilintide
CagriSema (with semaglutide), AM833
Main risk: Stomach side effects, and unverified online product
- Legal
- Not approved
- Cost a month
- No legal price
- A
Prescription
Liraglutide
Saxenda, Victoza
Main risk: Stomach side effects, plus rare serious events
- Legal
- Approved in all 4
- Cost a month
- About $1,350 list
- A
Research compound
Retatrutide
LY3437943, Reta
Main risk: Counterfeit or mislabelled product
- Legal
- Not approved
- Cost a month
- No legal price
- A
Prescription
Semaglutide
Wegovy, Ozempic
Main risk: Stomach side effects, plus rare serious events
- Legal
- Approved in all 4
- Cost a month
- $149 to $349
- A
Research compound
Survodutide
BI 456906
Main risk: Stomach side effects; about 1 in 5 stopped
- Legal
- Not approved
- Cost a month
- No legal price
- A
Prescription
Tirzepatide
Zepbound, Mounjaro
Main risk: Stomach side effects, plus rare serious events
- Legal
- Approved in all 4
- Cost a month
- $299 to $449
Smaller human trials
3- B
Research compound
Mazdutide
IBI362, OXM3
Main risk: Unapproved outside China, so online product is unverified
- Legal
- Not approved
- Cost a month
- No legal price
- B
Prescription
Setmelanotide
Imcivree, RM-493
Main risk: Skin and mole darkening in most users
- Legal
- Approved in US, UK, EU
- Cost a month
- Specialist use only
- B
Prescription
Tesamorelin
Egrifta, Egrifta WR
Main risk: Raised blood sugar and joint or muscle pain
- Legal
- Approved in US
- Cost a month
- Specialty price
Early or weak human data
2- C
Research compound
AOD-9604
Advanced Obesity Drug, hGH fragment 177-191
Main risk: Unknown safety, and evidence it does not work
- Legal
- Not approved
- Cost a month
- No legal price
- C
Research compound
CJC-1295
DAC:GRF, Modified GRF (1-29)
Main risk: Fast heart rate and flushing reactions reported
- Legal
- Not approved
- Cost a month
- No legal price