Independent peptide index

What appearance peptides really do, cost and risk.

Evidence grades, legal status and prices for the peptides people use for skin, fat loss, tanning and muscle. Written for people deciding what to believe, not what to buy.

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28 profiles · 78 sources · 0 sponsors

Behind every label is a molecule. We grade what it actually does.

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The index

28 profiles, one honest scale

Each profile puts the claim next to the evidence, the main risk, the legal status in four regions and what it costs. Sorted by evidence, never by popularity.

See all 28 profiles

PeptideGrade

Start with your goal

Skin7Wrinkles, firmness, hydrationCollagen peptides, GHK-Cu, Matrixyl, Argireline, Sermorelin, Epitalon, KPV Hair4Growth, thickness, lossCollagen peptides, GHK-Cu, Biotinoyl tripeptide-1, PTD-DBM Fat loss12Weight, appetite, leannessRetatrutide, Semaglutide, Tirzepatide, Liraglutide, Tesamorelin, AOD-9604, CJC-1295, Cagrilintide, Survodutide, Mazdutide, Setmelanotide, MOTS-c Tanning2Colour without the sunMelanotan II, Afamelanotide Muscle6Size, lean mass, strengthMK-677, Ipamorelin, CJC-1295, Sermorelin, MOTS-c, GHRP-6 Recovery5Injury, soreness, sleepBPC-157, MK-677, TB-500, Ipamorelin, KPV

Four evidence grades, and what they miss

A grade rates the proof for the claim, not safety or legality. Retatrutide earns an A and still has no legal retail product.

Large human trials

Big randomized trials with published or regulator-reviewed results.

Smaller human trials

Controlled trials exist, but they are small, mixed, sponsor-linked or in the wrong population.

Early or weak human data

Mostly lab or animal work, with tiny or poor-quality human studies.

Anecdote only

No meaningful human data for the product actually being sold.

Recent regulator changes

5 Nov 2026 · AustraliaLab tests found products labelled TB-500 with none detectableAustralia's regulator also found retatrutide products holding less than their labels stated.Read the TB-500 profile 28 Oct 2026 · United StatesHHS will tolerate compounding of six peptides, including BPC-157It is an interim enforcement policy, not an approval, and FDA's own drug centre recommended against listing them.Read the BPC-157 profile

Four rules that keep this index independent

No sales: We never sell peptides.
No sellers: No vendor links, affiliate links or discount codes.
No doses: No doses, cycles, stacks or protocols, anywhere.
No sponsors: Nobody pays to change a grade.

Read our editorial standards