Wrinkles, firmness, hydration
Peptides for skin
Sorted by strength of evidence, never by popularity. A higher grade means stronger proof, not that something is safe or right for you.
7 profiles
Smaller human trials
2- B
Supplement
Collagen peptides
Hydrolysed collagen, Collagen hydrolysate
Main risk: Mostly wasted money, and animal or fish allergens
- Legal
- Sold as a supplement
- Cost a month
- $12 to $40
- B
Skincare
Matrixyl
Palmitoyl pentapeptide-4, Pal-KTTKS
Main risk: Low risk. The main downside is paying for a small effect
- Legal
- Sold as a cosmetic
- Cost a month
- $10 to $50
Early or weak human data
3- C
Skincare
Argireline
Acetyl hexapeptide-8, Acetyl hexapeptide-3
Main risk: Low risk. The main downside is paying for hype
- Legal
- Sold as a cosmetic
- Cost a month
- $10 to $40
- C
Skincare
GHK-Cu
Copper peptide, Copper tripeptide-1
Main risk: Injected forms: immune reactions
- Legal
- Sold as a cosmetic
- Cost a month
- $15 to $60
- C
Prescription
Sermorelin
Geref, GHRH (1-29)
Main risk: Long-term safety in healthy adults unknown
- Legal
- Restricted in US
- Cost a month
- Clinic prices vary
Anecdote only
2- D
Research compound
Epitalon
Epithalon, AEDG peptide
Main risk: Unknown safety, and it switches on an enzyme cancers use
- Legal
- Restricted in US
- Cost a month
- Too new to price
- D
Research compound
KPV
Lys-Pro-Val, alpha-MSH (11-13)
Main risk: No human safety data at all
- Legal
- Restricted in US
- Cost a month
- Too new to price