lookindex

AOD-9604

Also known as Advanced Obesity Drug, hGH fragment 177-191

A failed obesity drug that lives on in clinics and online shops. Its developer ran human trials, and the biggest one did not beat placebo.

Information only. Not medical advice. Talk to a doctor before you start, stop or change anything.

What people claim

  • Burns fat without affecting muscle
  • The fat-burning part of growth hormone
  • No side effects

What the evidence shows

  • Its developer's phase 2b trial in obese adults failed to show efficacy, and development as an obesity drug was dropped.[1]
  • FDA says it has little or no safety information for compounded versions and has identified serious adverse events that may be linked, although causality is unclear.[2]

Known risks

  • FDA flags possible immune reactions, impurities and characterisation problems.[2]
  • Australian lab testing found unapproved peptide products that did not contain what their labels claimed.[3]
  • Banned in sport as a growth hormone fragment.[4]

Reported side effects

Moderated user reports are not open yet, so nothing is shown here. They will be labelled as unverified personal accounts.

Legal status

A summary, not legal advice. Rules change, and sport bans are separate.

United States

Unapproved

Not FDA approved and not covered by the October 2026 HHS compounding policy.[2][5]

United Kingdom

Unlicensed

No licensed medicine contains it.

Australia

Not approved

TGA says importing, advertising or supplying unapproved peptides is unlawful.[6]

European Union

Not authorised

No authorised medicine. National rules on possession and import differ.

Sources

  1. 1.Obesity pharmacotherapy: current perspectives and future directionsReview, PubMed Central
  2. 2.Bulk drug substances that may present significant safety risksUS FDA
  3. 3.TGA testing finds unapproved peptides do not contain what their labels claimTGA Australia, Nov 2026
  4. 4.The Prohibited List (section S2)World Anti-Doping Agency
  5. 5.HHS interim enforcement discretion policy for six peptides (legal summary)Holland & Knight, Nov 2026
  6. 6.Importing, compounding and supplying unapproved peptide productsTGA Australia

Profile last checked 7 Nov 2026.